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Drug Name

Pariet

Drug Uses

Pariet decreases the amount of acid produced in the stomach.

Pariet is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Pariet is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Pariet may also be given with an antibiotic to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori).

Pariet may also be used for other purposes not listed in this medication guide.

How to use

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Pariet is usually given for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time.

When treating H. pylori infection, Pariet may be needed for only 7 days. Follow your doctor's instructions.

Take this medicine with a full glass (8 ounces) of water.
Pariet may be taken with or without food.

Do not crush, break, or chew a Pariet tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or crushing the pill would cause too much of the drug to be released at one time. Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before your treatment is completed. Store Pariet at room temperature away from moisture and heat.

Drug Class and Mechanism

Pariet is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Pariet is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

Storage

Store Pariet at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pariet out of the reach of children and away from pets.

Warnings/Precautions

Do NOT use Pariet if:

* you are allergic to any ingredient in Pariet or to similar medicines (eg, omeprazole)
* you are taking an HIV protease inhibitor (eg, atazanavir)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Pariet:

Some medical conditions may interact with Pariet . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

* if you are pregnant, planning to become pregnant, or are breast-feeding
* if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
* if you have allergies to medicines, foods, or other substances
* if you have liver problems or stomach or bowel cancer


Some MEDICINES MAY INTERACT with Pariet . Tell your health care provider if you are taking any other medicines, especially any of the following:

* Clarithromycin or voriconazole because they may increase the risk of Pariet 's side effects
* Anticoagulants (eg, warfarin), cyclosporine, or digoxin because the risk of their side effects may be increased by Pariet
* Azole antifungals (eg, ketoconazole), clopidogrel, HIV protease inhibitors (eg, atazanavir), or iron because their effectiveness may be decreased by Pariet


This may not be a complete list of all interactions that may occur. Ask your health care provider if Pariet may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


Possible Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; fast or irregular heartbeat; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; severe or persistent stomach pain; unusual bruising or bleeding; unusual tiredness; vision changes.


More Information

Pariet may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Pariet with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.

Pariet may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Pariet.

Pariet should be used with extreme caution in Asian patients; the risk of side effects may be increased in these patients.

Pariet should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pariet while you are pregnant. It is not known if Pariet is found in breast milk. Do not breast-feed while taking Pariet .Warnings/Precautions

Do NOT use Pariet if:

* you are allergic to any ingredient in Pariet or to similar medicines (eg, omeprazole)
* you are taking an HIV protease inhibitor (eg, atazanavir)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Pariet:

Some medical conditions may interact with Pariet . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

* if you are pregnant, planning to become pregnant, or are breast-feeding
* if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
* if you have allergies to medicines, foods, or other substances
* if you have liver problems or stomach or bowel cancer


Some MEDICINES MAY INTERACT with Pariet . Tell your health care provider if you are taking any other medicines, especially any of the following:

* Clarithromycin or voriconazole because they may increase the risk of Pariet 's side effects
* Anticoagulants (eg, warfarin), cyclosporine, or digoxin because the risk of their side effects may be increased by Pariet
* Azole antifungals (eg, ketoconazole), clopidogrel, HIV protease inhibitors (eg, atazanavir), or iron because their effectiveness may be decreased by Pariet


This may not be a complete list of all interactions that may occur. Ask your health care provider if Pariet may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


Possible Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; fast or irregular